My mother started seeing a slight drop the next day. The dose has to be built up over a period of months, so it will take time for any real change. You should probably check with your pharmacist, as they will have a better idea of what you should expect.

Regarding the diarrhea, get some yogurt with live active culture in it, one that doesn't have any added sugar. There's one with Splenda which is quite good. You want a low carb yogurt with active culture.

Take a serving of this yogurt with your Metformin. That should stop the diarrhea. If it doesn't work, ask your doctor for time released Metformin. Its more expensive, but if the yogurt doesn't work, that should do it.

Also, try eating low carb, The South Beach Diet Book is a good place to start.

I hope you can get it to work for you, its the safest oral medication for diabetes available and has been around a long time. It has a good track record.

I had a very bad, rare reaction to it with the very first pill so I had to drop it.